Controversies in neuro-oncology : best-evidence medicine for by Alfredo Quinones-Hinojosa, Shaan M. Raza, Edward R. Laws

By Alfredo Quinones-Hinojosa, Shaan M. Raza, Edward R. Laws

In a quickly altering box with many new discoveries, a publication equivalent to this is often very helpful. Practitioners may perhaps simply get beaten through the masses of contradicting clinical articles, yet this ebook summarizes the literature and equips them to decide on the easiest methods for his or her sufferers. this can be a welcome boost to the sufferer care and clinical library. -- Doody agencies, Inc.

Because of super developments in learn, neurosurgical oncology has develop into more and more advanced, and it's valuable that physicians have medical facts to lead and protect their selection making as they attempt to supply the simplest sufferer care. Controversies in Neuro-Oncology: most sensible facts drugs for mind Tumor Surgery, written by way of world-renowned specialists, is a finished advisor that compiles, synthesizes, and summarizes the main proper clinical literature to be had in neurosurgical oncology. It offers aim concepts in accordance with the information present in the literature, giving physicians the knowledge they should make totally trained remedy decisions.

Key Features:

  • An starting bankruptcy, creation to top facts drugs, illustrates how the authors cost the viability of the knowledge presented
  • Authors talk about intimately in general disputed issues particular to tumor variety, akin to the jobs of surgical procedure and gross overall resection in addition to radiosurgery options
  • Expert suggestion bins spotlight takeaways for the reader
  • Summary tables distill ample medical proof and emphasize the most conclusions of released studies

This e-book may be the go-to advisor for all neurosurgeons, oncologists, and neurologists concerned about the multidisciplinary care of sufferers with mind tumors.

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Extra resources for Controversies in neuro-oncology : best-evidence medicine for brain tumor surgery

Example text

Summary and Conclusions GBM is the most common malignant primary brain tumor of adulthood. The management of GBM remains challenging, and the median survival remains less than 2 years despite advances in medical and surgical therapies. Currently, the standard treatment consists of maximal surgical resection, radiation, and chemotherapy. Surgery is critical in GBM management because it establishes diagnosis, relieves mass effect, and facilitates adjuvant therapies by reducing the residual tumor burden.

Defining the outcome and determining what is properly considered outcome is not easy. Parameters can include the following: the OS, the PFS, the rate of malignant transformation, the functional status of the patient and the improvement of preoperative neurological deficits or disturbances, such as seizure control, or the neuropsychological long-term outcome. Which of these are really indicative of, or should be considered as, a true clinical benefit? Are there studies properly addressing these issues in relation to surgical treatment?

Acta Neuropathol 2007;114(2):97–109 PubMed 3. Wen PY, Kesari S. Malignant gliomas in adults. N Engl J Med 2008;359(5):492–507 PubMed CHAPTER 3 ■ The Role of Surgery in the Management of High-Grade Gliomas 23 4. Chaichana KL, Parker SL, Olivi A, Quiñones-Hinojosa A. Longterm seizure outcomes in adult patients undergoing primary resection of malignant brain astrocytomas. Clinical article. J Neurosurg 2009;111(2):282–292 PubMed 5. Schwartzbaum JA, Fisher JL, Aldape KD, Wrensch M. Epidemiology and molecular pathology of glioma.

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