Comprehensive Organic Synthesis: Carbon-Carbon sigma-Bond by Trost B.M., Fleming I., Pattenden G. (eds.)

By Trost B.M., Fleming I., Pattenden G. (eds.)

Quantity three covers carbon-to-carbon unmarried bond forming reactions concerning sp 3, sp 2 and sp carbon facilities, yet simply these which don't contain additions to C-X &pgr;-bonds. the quantity first compares and contrasts the alkylation reactions of every kind of sp 3 carbon nucleophiles and in addition covers vinyl and alkynyl carbanions. Following on from quantity 2, a separate part covers Friedel-Crafts alkylation reactions, that's complemented by way of discussions of polyene cyclizations and electrophilic transannular cyclizations in synthesis. Coupling reactions resulting in &agr;-bond formation, and related to all kinds of mixtures of sp 3, sp 2 and sp carbon facilities are subsequent coated, together with these reactions in line with pinacol, acyloin and phenol oxidative coupling reactions, and likewise the Kolbe response. Rearrangement reactions, resulting in carbon-to-carbon &agr;-bond formation, are usually utilized in a smart demeanour in synthesis. the quantity comprises all these rearrangement reactions according to intermediate carbonium ions and carbanions, and likewise contains the benzil-benzilic acid and the Wolff rearrangements. the quantity closes with assurance of carbonylation reactions, and using carbene insertion reactions into the C-H bond in synthesis.

Show description

Read or Download Comprehensive Organic Synthesis: Carbon-Carbon sigma-Bond Formation PDF

Similar organic chemistry books

Microwaves in organic synthesis

Microwave expertise is turning into a extra appealing substitute for scientists facing natural synthesis from either an environmental and fiscal perspective. accordingly this well timed e-book will supply these chemists operating either in examine and with an crucial resource of data. comprises: targeted insurance of key themes together with microwave photochemistry, microwave know-how and kit and microwave and make contact with move catalysis Emphasis is given to the know-how used and comprises useful advice of software provides the most recent advancements within the box, written by means of a staff of across the world known specialists

Solvent-free Organic Synthesis (Green chemistry)

At the present time, with Google and technology Finder student, you might imagine that medical books have gotten out of date. whereas this can be real every so often, it really is on no account real for the "Solvent-Free natural Synthesis". This wonderful ebook is a testomony to the luck of the solvent-free reactions, that are one of many cornerstones of eco-friendly chemistry.

Additional resources for Comprehensive Organic Synthesis: Carbon-Carbon sigma-Bond Formation

Sample text

Oxidation dyeing was simply the in situ formation of a polymeric black or dark brown azine colorant of indeterminate constitution by acidic oxidation of a simple arylamine such as aniline or p-phenylenediamine on the fibre, using a chlorate or dichromate as oxidant and a copper salt catalyst. Although no longer significant in textile dyeing or printing, coloration techniques of a similar kind have remained the primary method of colouring human hair, feathers and natural furs. 16 Ingrain dyes This is another somewhat ambiguous category in the context of the Colour Index classification, but fortunately it is now merely of historical interest.

Accidents must have occurred frequently, reminding victims and supervisors alike of the penalties suffered if hazardous chemicals were handled carelessly. More insidious, however, were the potential health risks resulting from longer-term exposure to certain organic and inorganic chemicals. Operatives were expected to provide and wash their own working clothes. These must have become heavily contaminated with chemical stains, putting the worker’s family also at risk of exposure to hazardous vapours [65].

Operatives were expected to provide and wash their own working clothes. These must have become heavily contaminated with chemical stains, putting the worker’s family also at risk of exposure to hazardous vapours [65]. It was not until the 1940s that the connection was made between the high incidence of bladder cancer in employees of dye-making and dye-using firms and their exposure to certain arylamines, following epidemiological studies of individuals who had spent their working lives in these industries.

Download PDF sample

Rated 4.91 of 5 – based on 40 votes