Chronic Postsurgical Pain by Gérard Mick, Virginie Guastella

By Gérard Mick, Virginie Guastella

Primum non nocere… The indisputable fact that a surgery can depart any form of discomfort casts a shadow over this guiding principle, that is obvious because the foundation of scientific perform and anchor of its precept ethic…

It is the entire extra unbelievable in that drugs has purely paid consciousness to this paradoxical continual soreness scenario for the prior few years. Clarifying the information got during this box has turn into all of the extra pressing for any care-giver at the present time faced by way of a sound request from sufferers: Why and the way can a surgery, that is purported to deliver aid, depart in the back of an unacceptable sequela?

This is the technique which the individuals to this new topic of significant scientific curiosity invite you to persist with as you're employed your means via this book.

Show description

Read Online or Download Chronic Postsurgical Pain PDF

Similar neurosurgery books

Brain Tumors in Adults, An Issue of Neurologic Clinics

In 2007, among forty. 000 and 50,000 humans within the usa might be clinically determined with fundamental mind tumors, nearly all of whom could be adults. thrice this quantity will increase metastatic mind tumors from melanoma originating in different places within the physique. This factor of Neurologic Clinics comprises the subsequent articles: Epidemiology of mind Tumors (Wrensch, Claus); Molecular Pathogenesis of mind Tumors and the position of Stem Cells (Ligon, Kesari); Advances in Neuroimaging of mind Tumors (Henson); clinical administration of mind Tumor sufferers (Schiff, Wen); Advances in Neurosurgery for mind Tumors (Shaffrey); Advances in Radiation treatment for mind Tumors (Mehta); Novel remedies for mind Tumors (Wen, Schiff); Anaplastic Astrocytomas and Glioblastomas (Reardon); Anaplastic Oligodendrogliomas and Anaplastic Oligoastrocytomas (Van Den Bent); Low-Grade Gliomas (Lang, Gilbert); mind Metastases (Deangelis); Benign mind Tumors (Link); fundamental CNS Lymphoma (Abrey); and Genetic motives of mind Tumors (Plotkin).

Transendoscopic Ultrasound for Neurosurgery

Endoscopic neurosurgery has now not but reached the protection and applicability of microsurgery. Endo-neuro-sonography is a brand new strategy aimed toward making endoscopy more secure by means of real-time imaging and navigation capability (brain-radar). The endo-neurosonographic picture is a sonographic test on the tip of the endoscope (mini-CT) providing more information to the endoscopic view.

Handbook of Complex Percutaneous Carotid Intervention

This instruction manual vitamins hands-on education in interventional cardiology with a selected concentrate on percutaneous intervention in sufferers with extracranial carotid artery stenosis. It incorporates stories of landmark stories assisting carotid endarectomy and stenting and is a accomplished advisor to this interesting and burgeoning box.

Peripheral Nerve Surgery: Practical Applications in the Upper Extremity

This useful and complete ebook provide you with ultra-modern top wisdom at the remedy of nerve accidents from the brachial plexus to the fingertip. Pioneers in peripheral nerve surgical procedure from throughout North the United States and Europe provide you with guidance, pearls, and technical issues gleaned from their many years of expertise.

Additional info for Chronic Postsurgical Pain

Example text

Thus in animals, the occurrence of non-nociceptive postoperative environmental stress is capable of inducing, not analgesia as is observed in rats that have not undergone surgery, but hyperalgesia lasting for several hours, or even several days if the stresses are repeated (Fig. 4) [1]. Other Pharmacological Factors are Also Likely to Give Rise to Hypersensitivity to Pain Although all these experimental and clinical data confirm that the activation of opioid systems, even briefly (acutely), can play a major role as a predisposing factor for the development of latent hypersensitivity to pain, it is noticeable that this phenomenon is probably not specific to opioid systems.

These results indicate that as in the case of pain, administration of an opioid may give rise to hypersensitivity to anxiogenic situations over a long period, which is a biological vulnerability. e. NMDA antagonists, also completely prevent this vulnerability to anxiogenic situations [26] (Le Roy, unpublished data). From Normal to Pathological: Hypersensitivity, a General Process of Adaptation in Evolutionary Terms? Although this is speculative at present, these data suggest some consideration of the view that the use of analgesic opioids, like the release of endogenous opioids peptides may, in addition to their immediate, desirable, analgesic or anxiolytic effects, also induce functional remodelling of the central nervous system which takes the form of hypersensitivity both to internal events and to external environmental events (tissue injuries, stress), leading to a perception of pain or an anxiety response.

1007/978-3-319-04322-7_4, Ó Springer International Publishing Switzerland 2014 41 42 C. Dualé • Nerve injury thus appears to be an essential but not sufficient factor for the development of CPSP, while other factors, mostly genetic and biographical in nature, are superimposed upon it. Confounding Factors The Nature of Nerve Injuries Although it is reasonable to suppose that certain operations do cause peripheral nerve injuries (see below), the precise nature of these injuries is very poorly understood.

Download PDF sample

Rated 4.37 of 5 – based on 39 votes