Cerebral Hemorrhage by Liang-Fu Zhou, Guohua Xi, Xian-Cheng Chen, Richard F. Keep,

By Liang-Fu Zhou, Guohua Xi, Xian-Cheng Chen, Richard F. Keep, Feng-Ping Huang, Ya Hua, Yi-Cheng Lu, Karin Muraszko

Cerebral hemorrhage is a standard and sometimes deadly subtype of stroke. whereas some time past it has bought rather little recognition in comparison to ischemic stroke, there were significant advances in our knowing of this devastating type of stroke. The papers through global specialists disguise the sector from molecular biology to scientific trials.

Show description

Read or Download Cerebral Hemorrhage PDF

Best neurosurgery books

Brain Tumors in Adults, An Issue of Neurologic Clinics

In 2007, among forty. 000 and 50,000 humans within the usa could be clinically determined with basic mind tumors, nearly all of whom might be adults. thrice this quantity will advance metastatic mind tumors from melanoma originating in other places within the physique. This factor of Neurologic Clinics comprises the next articles: Epidemiology of mind Tumors (Wrensch, Claus); Molecular Pathogenesis of mind Tumors and the function of Stem Cells (Ligon, Kesari); Advances in Neuroimaging of mind Tumors (Henson); scientific administration of mind Tumor sufferers (Schiff, Wen); Advances in Neurosurgery for mind Tumors (Shaffrey); Advances in Radiation treatment for mind Tumors (Mehta); Novel cures for mind Tumors (Wen, Schiff); Anaplastic Astrocytomas and Glioblastomas (Reardon); Anaplastic Oligodendrogliomas and Anaplastic Oligoastrocytomas (Van Den Bent); Low-Grade Gliomas (Lang, Gilbert); mind Metastases (Deangelis); Benign mind Tumors (Link); fundamental CNS Lymphoma (Abrey); and Genetic explanations of mind Tumors (Plotkin).

Transendoscopic Ultrasound for Neurosurgery

Endoscopic neurosurgery has now not but reached the protection and applicability of microsurgery. Endo-neuro-sonography is a brand new strategy geared toward making endoscopy more secure through real-time imaging and navigation capability (brain-radar). The endo-neurosonographic snapshot is a sonographic test on the tip of the endoscope (mini-CT) providing more information to the endoscopic view.

Handbook of Complex Percutaneous Carotid Intervention

This instruction manual vitamins hands-on education in interventional cardiology with a selected concentrate on percutaneous intervention in sufferers with extracranial carotid artery stenosis. It includes studies of landmark stories aiding carotid endarectomy and stenting and is a complete advisor to this interesting and burgeoning box.

Peripheral Nerve Surgery: Practical Applications in the Upper Extremity

This sensible and entire ebook will give you latest most sensible wisdom at the therapy of nerve accidents from the brachial plexus to the fingertip. Pioneers in peripheral nerve surgical procedure from throughout North the USA and Europe give you guidance, pearls, and technical issues gleaned from their a long time of expertise.

Extra resources for Cerebral Hemorrhage

Example text

During autophagy, LC3-II is increased by conversion from LC3-I [7]. MDC is a specific marker for autophagic vacuoles [2]. Materials and methods Animal preparation and intracerebral injection The University of Michigan Committee on the Use and Care of Animals approved the protocols for these studies. Male Sprague-Dawley rats weighing 275 to 350 g (Charles River Laboratories, Portage, MI) were used. ). A polyethylene catheter (PE-50) was then inserted into the right femoral artery to monitor arterial blood pressure and blood gases.

There is evidence showing that oxidative stress can induce autophagic cell death [3]. In this study, therefore, we investigated whether iron can induce autophagy in neurons. Two markers for autophagy, microtubule-associated protein light chain-3 (LC3) and fluorescent dye monodansylcadaverine (MDC), were used. LC3 is a marker for autophagosomes. LC3 has 2 forms: type I is cytosolic and type II is membranebound. During autophagy, LC3-II is increased by conversion from LC3-I [7]. MDC is a specific marker for autophagic vacuoles [2].

Iron toxicity is largely based on Fenton chemistry, where iron reacts with reactive oxygen intermediates, including hydrogen peroxide (H2O2) and the superoxide anion (OÀ 2 ) – both byproducts of aerobic metabolism – to produce highly reactive free radical species such as the hydroxyl radical (OH). The overwhelming production of free radicals, as well as lipid peroxidation induced by hemoglobin itself and its breakdown product, iron, which includes ROS and RNS, results in tissue damage, lipid peroxidation of cell membranes, and protein oxidation.

Download PDF sample

Rated 4.38 of 5 – based on 34 votes