Biodefence: Advanced Materials and Methods for Health by Sergey Mikhalovsky, Abdukhakim Khajibaev

By Sergey Mikhalovsky, Abdukhakim Khajibaev

This e-book specializes in defence opposed to organic war with an emphasis on purposes of contemporary applied sciences and complicated fabrics in detection, future health defense and scientific therapy of the inhabitants. particular subject matters comprise high-throughput delicate detection equipment, complicated nanostructured fabrics and methods for exterior and inner safeguard of human future health, in addition to extracorporeal tools, adsorptive fabrics and bacteriophages decontaminating the human organism, and neutralising integrated CBRN brokers. The contributions describe contemporary advancements within the box of biodefence geared toward preserving inhabitants opposed to terrorism and terror similar occasions. Broader techniques to decreasing the influence of environmental toxins on human well-being and enhancing potency of clinical therapy of sufferers with viral infections, poisoning and organ failure also are mentioned.

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Additional info for Biodefence: Advanced Materials and Methods for Health Protection (NATO Science for Peace and Security Series - A: Chemistry and Biology)

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1 Introduction High surface area nanoporous carbon (NPC) is a sorbent used almost ubiquitously both in liquid and gas phase applications ranging from drinking/waste water ­treatment, industrial or chemical/biological warfare protection to clinical treatment of acute poisoning cases by haemoadsorption. Different types of molecule occupy adsorption sites that depend on the polarity and on the surface treatment of the ­substrate. Furthermore, extraneous molecules, notably water vapour, can compete with other target molecules, hence compromising the role of the carbon.

The data obtained show that crude nanotubes possess a certain level of toxicity (in both in vivo and in vitro studies) associated mainly with the presence of metals, which are used as catalysts in nanotube synthesis. For purified nanotubes minimal toxic effects were seen even at high concentrations, and chemically functionalized nanotubes used for drug delivery did not show any toxic effects. However, the ability of nanotubes to form aggregates requires further research in this area. From the data obtained so far one could conclude that work with nanotubes should be done with precaution, and certain safety actions need to be considered working with nanotubes in laboratories and during their manufacture.

Springer, pp 425–441 12. Kharlamov AI,K Kirillova NV, Zaytseva ZA (2007) Novel state of carbon: transparent threadlike anisotropic crystals. Proc Ukr Acad Sci 5:101–106 13. Pul Ch, Owens F (2005) Nanotechnology. Tekhnosfera, Moscow, Russia 14. Hoet P, Bruske-Holfeld I, Salata O (2004) Nanoparticles – known and unknown health risks. J Nanobiotech 2:12–18 15. Oberdörster G, Oberdörster E, Oberdörster J (2005) Nanotoxicology: an emerging discipline from studies of ultrafine particles. Environ Health Perspect 113:823–839 16.

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